Erythromycin breath test predicts oral clearance of cyclosporine in kidney transplant recipients

The erythromycin breath test predicts the clearance of midazolam.

Midazolam, a commonly used sedative and amnestic medication, has recently been shown to be largely metabolized in the liver by a cytochrome P450, termed CYP3A4. There is at least a tenfold intersubject variability in the liver content and catalytic activity of CYP3A4, which may in part account for the known interpatient differences in the kinetics of midazolam. To test this hypothesis, we deter...

cyclosporine absorption in kidney transplant recipients

I - Clinical Details in 5 Liver Transplant Recipients at Time of Erythromycin Breath Test

low flow to the left hemisphere. These indications of low neural activity in the left hemisphere are consistent with early reports on lateralised features in the EEG in dysphasia.17 In conclusion, we have shown that various developmental learning disabilities are associated with regional cerebral blood flow abnormalities as assessed with SPET. It may be that the phylogenetically recent linguist...

Oral Lesions in Kidney Transplant Recipients

Permanent immunosuppression is necessary to prevent rejection after kidney transplantation. However, it may predispose patients to different conditions and diseases including oral lesions. The most common benign oral lesions in kidney transplant recipients are gingival hyperplasia, oral candidiasis, hairy leukoplakia and saburral tongue. Oral form of Kaposi sarcoma, although rarely, can also be...

Electrolytes Disturbance and Cyclosporine Blood Levels among Kidney Transplant Recipients

BACKGROUND Kidney transplantation is associated with various biochemical abnormalities such as changes in serum blood level of sodium (Na), potassium (K), calcium (Ca), and phosphorous (P). Although cyclosporine (CsA) is used commonly, the prevalence of its side effects, including electrolytes disturbance, is not well understood. OBJECTIVE To find the prevalence of electrolytes disturbance an...